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Trust pills: Birth Control Pill Proven to Be 99% Effective!

ADC
October 28, 2023
11:16 am

Trust pills are a brand-name combined oral contraceptive pill (COC) manufactured in Philippines. They contain two hormones: ethinylestradiol, an estrogen, and levonorgestrel, a progestin.

COCs work by preventing ovulation and thickening the cervical mucus, making it more difficult for sperm to reach the egg. They are one of the most effective forms of contraception available, with a failure rate of less than 1% when taken perfectly.

Trust pills: Birth Control Pill Proven to Be 99% Effective!

Trust pills are also used to treat menstrual disorders such as dysmenorrhea (painful menstruation), premenstrual syndrome (PMS), and menorrhagia (heavy menstrual bleeding).

Each pack of Trust pills contains 28 tablets: 21 active tablets containing ethinylestradiol and levonorgestrel, and 7 inactive tablets containing ferrous fumarate (iron). The active tablets are taken once daily for 21 days, followed by the inactive tablets for 7 days. During the 7 days on the inactive tablets, menstrual bleeding typically occurs.

Description

Each of the 21 ochreous tablets contains: Ethinyl Estradiol 30 mcg, Levonorgestrel 125 mcg.
Each of the 7 brown tablets contains: Ferrous Fumarate 75 mg (equivalent to 24.75 mg of elemental iron).
Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL) is a safe and easy to use contraceptive pill.

It is also used in the treatment of menstrual disorders such as painful menstruation, menstrual cycle symptoms, and excessive uterine bleeding. It contains Iron that helps improve the hemoglobin level of blood during menstruation.
Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL) does not delay the return of fertility after discontinuing its use.

Generally, the patient’s bleeding pattern before taking Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL) will return after the patient discontinue taking it. Some women, however, may have to wait a few months before their usual bleeding pattern returns.

Action

Pharmacology: Pharmacodynamics: Mechanism of action: Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL) works primarily by preventing the release of eggs from the ovaries. Also, ethinyl estradiol acts synergistically with levonorgestrel to provide regular and consistent suppression of ovulation.

Pharmacokinetics: Ethinyl Estradiol is absorbed well and rapidly by the gastrointestinal tract.

The presence of an Ethinyl group at the 17-position greatly reduces hepatic first-pass metabolism compared with Estradiol, enabling the compound to be much more active if taken orally. There is some initial conjugation at the gut wall, and the systemic bioavailability is only 40%. Ethinyl Estradiol is highly protein bound, unlike naturally occurring estrogens, which are mainly bound to sex hormone-binding globulin; it is principally bound to albumin. It is metabolized in the liver, and excreted in the urine and feces. Metabolites undergo enterohepatic recycling.

Levonorgestrel is rapidly and almost completely absorbed after being taken orally and undergoes little first-pass hepatic metabolism. It is highly bound to plasma proteins; 42% to 68% to sex hormone-binding globulin and 30% to 56% to albumin. The proportion bound to sex hormone-binding globulin is higher when it is given with an estrogen. Levonorgestrel is metabolized in the liver to sulfate and glucuronide conjugates, which are excreted in the urine and to a lesser extent in the feces.

Indications/Uses

Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL) is indicated for contraception and treatment of menstrual disorders such as dysmenorrhea, premenstrual syndrome, and menorrhagia.

Dosage/Direction for Use

Talk to a healthcare provider before taking Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL).
Take one pill daily, beginning on the first day of menstrual bleeding. Patient can also start any day as long as patient is not pregnant and use a back-up method such as condom for the next seven days as a precaution to avoid pregnancy. Start with the pill marked number “1”. Follow the arrows indicated on the pack.

The interval between two pills should be 24 hours. Incorporate it to patient’s daily routine – after eating meals or before going to sleep so patient can easily remember to take it. A pack is good for 28 days.

Start a new pack the next day after taking the last brown pill regardless whether the patient’s menstrual bleeding has stopped or not. Patient’s menstrual period will return to normal two days after finishing the ochreous pills and while taking the brown pills.

Patient may continue taking the pill as long as the patient wants to avoid pregnancy. Do not skip taking the pill even if there is a brief pause from sexual activity.
Patient should only stop taking the pill after finishing a pack; otherwise, bleeding may start.
Vomiting and persistent severe diarrhea can interfere with the absorption of the pill.

If vomiting occurs within two hours after taking a pill, another pill should be taken as soon as possible. If persistent vomiting and diarrhea last more that 24 hours, follow the instructions on Missed Pills.

Missed Pills: The key to effective contraception is following the recommended dosage consistently.
If the patient missed one ochreous pill, take it as soon as remembered. Take the pill due for the day at the regular time even if it means taking two pills in one day. Keep taking one pill each day at the usual time. Patient will not need a back-up contraceptive method if only one pill is missed.

Missing two or more ochreous pills consecutively increases the probability of getting pregnant. Take the most recently missed ochreous pill as soon as remembered and discard all remaining previously missed pills. Resume taking the next scheduled pill and either abstain from sex or use condoms for the next seven days. Count the ochreous pills left in the pack.

If one to six ochreous pills are left in the pack, finish the remaining ochreous pills and discard all brown pills. Start a new pack immediately and use condoms for the next seven days. Bleeding may not come at the regular time.
If there are seven or more ochreous pills left in the pack, continue taking the contents of the pack including the brown pills. Start with a new pack.

If patient continually forgets to take the pills, ask the healthcare provider for ways to become compliant, or for another method of contraception which will suit better.

What to do if patient missed taking the brown pill: Patient does not have to worry if the brown pill is missed as long as the patient finished the pack which completes the 28-day cycle. The brown pill contains Ferrous Fumarate, an Iron supplement, that helps improve the hemoglobin of blood during menstruation.

Overdosage

No serious ill effects have been reported after ingestion of large doses of oral contraceptives, although it may cause nausea and withdrawal bleeding in females. Treatment is unnecessary because the overdose is unlikely to be life-threatening. Ask a healthcare provider for further instructions.

Contraindications

Make sure the patient is not pregnant before taking Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL). Patient should inform the healthcare provider if she has the following conditions before taking Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL): liver disorders, clotting disorders, breast and cervical cancer, sickle-cell anemia, hormone-active tumors, hyperlipidemia, severe cardiovascular diseases, previous or existing thromboembolic diseases, idiopathic jaundice.

Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL) is not recommended for pregnant women.
Breastfeeding mothers should not use Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL). This may reduce the volume of the breast milk. Breastfeeding mothers can use progestin-only pills.

Precautions about Trust pills

Regular consultation with a healthcare provider is recommended while taking Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate (TRUST PILL). If patient suffers from diarrhea and/or vomiting, its efficacy may be reduced. Inform the healthcare provider if the patient is suffering from the following conditions: diabetes mellitus, high blood pressure, varicose veins, multiple sclerosis, epilepsy, migraine, ophthalmological problems, tetany.

Adverse Reactions

The oral contraceptive pill is the most researched product in the history of modern medicine, and its safety has long been established. Some women may experience side effects such as headache, gastric upsets, nausea, vomiting, abdominal cramps, changes in appetite, breast tenderness, change in body weight and libido, depressive moods, or interference with liver functions.

Drug Interactions

Taking drugs for infection (such as ampicillin, chloramphenicol, neomycin, penicillin V, nitrofurantoin, sulfonamides, tetracycline and isoniazid) and pain (analgesic, anti-migraine and tranquilizer) with contraceptive pill may decrease the contraceptive’s efficacy. If the patient is advised to take the previously mentioned drugs, consult a healthcare provider for proper intake and dosage schedule of the contraceptive pill.

Taking contraceptive pills and anti-infective drugs (such as clarithromycin, erythromycin, itraconazole, ketoconazole, ritonavir) or grapefruit juice may inhibit cytochrome P-450 isoenzyme 3A4. Adverse effects may be seen upon taking these drugs.

Taking oral contraceptive pills and drugs that induce hepatic enzyme such as anti-epileptic drugs (carbamazepine, oxcarbazepine, felbamate, topiramate, phenytoin), anti-fungal (griseofulvin), anti-diabetic (troglitazone), musculoskeletal (phenylbutazone), and anti-tuberculosis (rifampicin) drugs can considerably reduce the contraceptive’s efficacy.
Taking contraceptives and troleandomycin may increase the risk of cholestatic jaundice.

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Frequent Asked Questions about Trust Pills

What are Trust pills?

Trust pills are a brand-name combined oral contraceptive pill (COC) manufactured by DKT Philippines. They contain two hormones: ethinylestradiol, an estrogen, and levonorgestrel, a progestin.

How do Trust pills work?

COCs work by preventing ovulation and thickening the cervical mucus, making it more difficult for sperm to reach the egg.

How effective are Trust pills?

Trust pills are very effective at preventing pregnancy, with a failure rate of less than 1% when taken perfectly.

Can Trust pills be used to treat menstrual disorders?

Yes, Trust pills can also be used to treat menstrual disorders such as dysmenorrhea (painful menstruation), premenstrual syndrome (PMS), and menorrhagia (heavy menstrual bleeding).

How do I take Trust pills?

Trust pills are taken once daily for 21 days, followed by 7 days of inactive pills. The active tablets are taken once daily for 21 days, followed by the inactive tablets for 7 days. During the 7 days on the inactive tablets, menstrual bleeding typically occurs.

What are the side effects of Trust pills?

Trust pills are generally safe and well-tolerated, but they can cause side effects such as nausea, vomiting, breast tenderness, headache, and mood swings. More serious side effects, such as blood clots and stroke, are rare.

Who should not take Trust pills?

Trust pills should not be taken by women who are pregnant, have a history of blood clots, or have certain medical conditions such as liver disease or heart disease.

Do I need a prescription for Trust pills?

Yes, Trust pills are a prescription medication, so you will need to see a doctor to get a prescription.

Can I breastfeed while taking Trust pills?

No, it is not recommended to breastfeed while taking Trust pills. Trust pills can reduce the volume of breast milk and may also pass into the breast milk.

What should I do if I miss a pill?

If you miss a pill, take it as soon as you remember. If you are more than 12 hours late taking a pill, take two pills at once. Then, continue taking your pills as usual. If you miss more than two pills in a row, contact your doctor.

Summary

Here are some tips to keep in mind about Trust pills:

Trust pills are a prescription medication, so you will need to see a doctor to get a prescription.
Trust pills are a combined oral contraceptive, so they contain both estrogen and progestin.
Trust pills are taken once daily for 21 days, followed by 7 days of inactive pills.
Trust pills are very effective at preventing pregnancy, but they are not 100% effective.
Trust pills can also be used to treat menstrual disorders such as dysmenorrhea, PMS, and menorrhagia.
Trust pills are generally safe and well-tolerated, but they can cause side effects such as nausea, vomiting, breast tenderness, headache, and mood swings. More serious side effects, such as blood clots and stroke, are rare.
Trust pills should not be taken by women who are pregnant, have a history of blood clots, or have certain medical conditions such as liver disease or heart disease.

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