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Synaleve Capsule – Relieve Pain and Inflammation

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Synaleve Capsule is primarily used for joint pain, relief of mild to moderate pain, headache, toothache, periods pain, flu, short-term anxiety, ear pain, and fever.
It contains Codeine Phosphate, Meprobamate, and Paracetamol as active ingredients, working by increasing the blood flow across the skin.
Synaleve Capsule may also be used for purposes not listed in this medication guide.
Synaleve Capsule
Synaleve Capsule
Synaleve Capsule contains Codeine Phosphate, Meprobamate and Paracetamol as active ingredients.
Synaleve Capsule works by broken down by the liver into morphine; affecting certain areas of the brain; increasing the pain threshold and increases the blood flow across the skin, heat loss and sweating;
Detailed information related to Synaleve Capsule’s uses, composition, dosage, side effects and reviews is listed below.


Synaleve Capsule is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
  • Joint pain
  • Relief of mild to moderately severe pain
  • Headache
  • Toothache
  • Periods pain
  • Flu
  • Short-term anxiety
  • Mild to moderate pain
  • Ear pain
  • Fever
  • Synaleve Capsule may also be used for purposes not listed here.


The following is a list of possible side-effects that may occur from all constituting ingredients of Synaleve Capsule. This is not a comprehensive list.
These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
  • Drowsiness
  • Constipation
  • Feeling of sickness
  • Sweating
  • Dizziness
  • Abdominal cramps
  • Anxiety
  • Depression
  • Headache
  • Fatigue
  • Nausea
  • Rashes
  • Blurred vision
  • Sedation
  • Feeling sick or being sick
  • Palpitations
  • Loss of appetite
  • Dry mouth
  • Lightheadedness
  • Vomiting
  • Difficulty breathing
  • Facial flushing
  • Mental confusion
  • Shortness of breath
  • Allergic reactions
  • Euphoria
  • Dysphoria
  • Abdominal pain
  • Pruritis
  • Faintness
  • Flushing
  • Hypotension
  • Syncope
  • Anorexia
  • Diarrhea
  • Gastrointestinal distress
  • Pancreatitis
  • Insomnia
  • Nervousness
  • Shakiness
  • Somnolence
  • Vertigo
  • Visual disturbances
  • Weakness
  • Rash
  • Respiratory depression
  • Circulatory depression
  • Respiratory arrest
  • Shock
  • Cardiac arrest
  • Abnormal skin sensations
  • Skin reddening
  • Swollen facial features
  • Liver damage
  • Abnormalities of blood cells
  • Liver toxicity
  • Less white blood cells
  • Acute renal tubular necrosis
  • Blood dyscrasias
  • Synaleve Capsule may also cause side-effects not listed here.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.


Before using Synaleve Capsule, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.).
Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert.
Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
  • Acute pancreatitis
  • Addison’s disease
  • Avoid alcohol consumption
  • Avoid driving a car or operating machinery
  • Avoid taking alcohol or other central nervous system depressants
  • Avoid using it if allergic to paracetamol
  • Biliary tract disease
  • Constipation is a side effect and can be relieved by stool softeners
  • Consult doctor if pregnant or nursing
  • Death in patients who have multiple copies of the gene for cytochrome P450 isoenzyme 2D6

Interactions with Synaleve Capsule

If you use other drugs or over the counter products at the same time, the effects of Synaleve Capsule may change. This may increase your risk for side-effects or cause your drug not to work properly.
Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions.
Synaleve Capsule may interact with the following drugs and products:
  • Alcohol
  • Antianxiety agents
  • Anticholinergics
  • Antiemetics
  • Antihistamines
  • Antipsychotics
  • General anesthetics
  • Hypnotics
  • Interfere with certain laboratory tests
  • Juxtapid mipomersen

When not to use Synaleve Capsule

Hypersensitivity to Synaleve Capsule is a contraindication. In addition, Synaleve Capsule should not be used if you have the following conditions:
  • Acute or severe bronchial asthma
  • Children under the age of 6 years
  • Hepatic impairment
  • Hypercarbia
  • Hypersensitivity
  • Hypersensitivity to codeine
  • Paralytic ileus
  • Porphyria
  • Postoperative pain management in children who have undergone tonsillectomy or adenoidectomy
  • Respiratory depression in the absence of resuscitative equipment

Composition and Active Ingredients

Synaleve Capsule is composed of the following active ingredients
  • Codeine Phosphate – 8Mg
  • Meprobamate – 200Mg
  • Paracetamol – 400Mg
Please note that this medicine may be available in various strengths for each active ingredient listed above.

Packages and Strengths

Synaleve Capsule is available in the following packages and strengths
Synaleve Capsule – Packages: 100, 40

Frequently Asked Questions

  • Is Synaleve Capsule safe to use when pregnant?
    • Codeine Phosphate: No
    • Meprobamate: Please consult with your doctor for case-specific recommendations.
    • Paracetamol: Please consult with your doctor for case-specific recommendations.


  • Is Synaleve Capsule safe while breastfeeding?
    • Codeine Phosphate: Please discuss the risks and benefits with your doctor.
    • Meprobamate: No
    • Paracetamol: Please discuss the risks and benefits with your doctor.


  • Can Synaleve Capsule be used for joint pain and relief of mild to moderately severe pain?
    Yes, joint pain and relief of mild to moderately severe pain are among the most common reported uses for Synaleve Capsule. Please do not use Synaleve Capsule for joint pain and relief of mild to moderately severe pain without consulting first with your doctor.


  • How long do I need to use Synaleve Capsule before I see improvement of my conditions?
    Users have reported within 2 hours and same day as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Synaleve Capsule.


  • At what frequency do I need to use Synaleve Capsule?
    Thrice a day and once a day as the most common frequency of using Synaleve Capsule. Please follow your doctor’s advice on how often you need to Synaleve Capsule. Click here and view survey results to find out what other patients report as frequency of using Synaleve Capsule.


  • Is it safe to drive or operate heavy machinery when using this product?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Synaleve Capsule medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Synaleve Capsule. Always consult with your doctor for recommendations specific to your body and health conditions.


  • Is this medicine or product addictive or habit forming?
    Most medicines don’t come with a potential for addiction or abuse. Usually, the government’s categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body’s dependence to medicines without the advice of a doctor.


  • Can i stop using this product immediately or do I have to slowly wean off the use?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Synaleve Capsule

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.

Overdosage of Synaleve Capsule

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Synaleve Capsule, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.

Storage of Synaleve Capsule

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Synaleve Capsule.

Expired Synaleve Capsule

  • Taking a single dose of expired Synaleve Capsule is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drugs. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.



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