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Staphylex (flucloxacillin) 500mg: Effective Drug Against Infections

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Staphylex (flucloxacillin) 500mg is a brand-name prescription medication that contains the active ingredient flucloxacillin. It is a narrow-spectrum antibiotic that is used to treat infections caused by certain types of bacteria, including penicillinase-producing Staphylococcus aureus (PSSA). PSSA is a type of staph bacteria that is resistant to some penicillin antibiotics.

Uses of Staphylex 500

Staphylex 500 can be used to treat a variety of infections caused by PSSA, including:

  • Pneumonia
  • Skin and soft tissue infections
  • Bone and joint infections
  • Ear infections
  • Sinus infections
  • Dental infections
  • Urinary tract infections
  • Sepsis

How does Staphylex 500 work?

Staphylex 500 works by killing bacteria, interfering with the cell wall formation. The cell wall is essential for the survival of bacteria, so when it is disrupted, the bacteria die.

Staphylex (flucloxacillin) 500mg: Effective Drug Against Infections
Staphylex (flucloxacillin) 500mg: Effective Drug Against Infections

Dosage and administration of Staphylex 500

The dosage of Staphylex 500 will vary depending on the type and severity of the infection, as well as the patient’s age and weight. The usual dosage for adults is 250mg to 500mg every 6 hours. Children may be given a lower dose, depending on their age and weight.

Staphylex 500 can be taken with or without food. However, it is important to take the medication at the same time each day to maintain a consistent level of the drug in the bloodstream.

The duration of treatment with Staphylex 500 will also vary depending on the type and severity of the infection. The usual duration of treatment is 7 to 10 days. However, some infections may require longer treatment.

How to take Staphylex 500

Staphylex 500 is available in capsule form. The capsules should be swallowed whole with water. Do not chew or crush the capsules.

If you are having trouble swallowing the capsules, you can open them and sprinkle the contents onto a spoonful of food or drink. Be sure to swallow all of the food or drink to ensure that you get the full dose of the medication.

When to take Staphylex 500

Staphylex 500 should be taken every 6 hours, even at night. It is important to take the medication at the same time each day to maintain a consistent level of the drug in the bloodstream.

If you miss a dose of Staphylex 500, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with the next dose.

How long to take Staphylex 500

The duration of treatment with Staphylex 500 will vary depending on the type and severity of the infection. The usual duration of treatment is 7 to 10 days. However, some infections may require longer treatment.

Side effects of Staphylex 500

The most common side effects of Staphylex 500 are mild and go away on their own. These side effects may include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach upset
  • Rash
  • Hives

Less common side effects of Staphylex 500 include:

  • Liver damage
  • Kidney damage
  • Allergic reactions (including anaphylaxis)
  • Superinfection (infection caused by bacteria that are not killed by the antibiotic)

If you experience any side effects while taking Staphylex 500, be sure to contact your doctor.

Drug interactions of Staphylex 500

Staphylex 500 can interact with certain other medications, including:

  • Probenecid
  • Warfarin
  • Methotrexate
  • Aspirin
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

If you are taking any other medications, be sure to tell your doctor before starting Staphylex 500.

Contraindications of Staphylex 500

Staphylex 500 should not be taken by people who are allergic to penicillin antibiotics or to any of the ingredients in Staphylex 500.

Special warnings and precautions for Staphylex 500

Staphylex 500 and pregnancy

Staphylex 500 is safe to take during pregnancy. However, it is important to talk to your doctor before taking any medication, including Staphylex 500, while you are pregnant.

Staphylex 500 and breastfeeding

Staphylex 500 passes into breast milk. However, the amount of the drug that is passed into breast milk is very small and is not likely to harm a nursing infant. If you are breastfeeding, talk to your doctor before taking Staphylex 500.

Staphylex 500 and liver disease

Staphylex 500 can worsen liver damage in people with pre-existing liver disease. If you have liver disease, talk to your doctor before taking Staphylex 500.

Staphylex 500 and kidney disease

Staphylex 500 can worsen kidney damage in people with pre-existing kidney disease. If you have kidney disease, talk to your doctor before taking Staphylex 500.

Before you take STAPHYLEX

WARNING: flucloxacillin can cause severe liver damage, particularly in older patients and those who take it for more than 14 days.

When you should not take it

Do not take STAPHYLEX if you have an allergy to:
  • any medicine containing flucloxacillin
  • any other penicillin medicines or cephalosporins
  • beta-lactam antibiotics including imipenem and aztreonam
  • any of the ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include:
  • shortness of breath
  • wheezing or difficulty in breathing
  • swelling of the face, lips, tongue or any other parts of the body
  • rash, itching or hives on the skin
Do not take STAPHYLEX if you have had a reaction affecting your liver while you were taking a medicine containing flucloxacillin.
Examples of liver reactions include hepatitis and jaundice (yellowing of the eyes or skin).
Do not use this medicine in your eyes.
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.
If it has expired or is damaged, return to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.

Before you start to take it

Tell your doctor if you have or have had any of the following medical conditions:
  • liver problems
  • kidney problems
  • jaundice, yellowing of the skin or eyes
  • asthma, hayfever, eczema or other allergic conditions.
Tell your doctor if you are pregnant or plan to become pregnant or are breast-feeding.
Your doctor can discuss with you the risks and benefits involved.
The active ingredient in STAPHYLEX passes into breast milk and there is a possibility that your baby may be affected.
If you have not told your doctor about any of the above, tell them before you start taking STAPHYLEX.

Taking other medicines

Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Tell your doctor or pharmacist if you are taking this medicine in combination with paracetamol, particularly if you have impaired kidney function.
Some medicines and STAPHYLEX may interfere with each other. These include:
  • probenecid (e.g. Pro-Cid), a medicine commonly used to treat gout
  • oral contraceptive pills, medicines used for contraception
You should use other birth control methods while you are taking STAPHYLEX.
These medicines may be affected by STAPHYLEX or may affect how well it works. You may need different amounts of your medicine, or you may need to take different medicines. Your doctor or pharmacist has more information on medicines to be careful with or avoid whilst taking this medicine.

Storage and disposal of Staphylex 500

Staphylex 500 capsules should be stored at room temperature, away from moisture and heat. Keep Staphylex 500 out of the reach of children and pets.

If you have any unused Staphylex 500 capsules, flush them down the toilet or dispose of them in a safe manner, following the instructions provided by your pharmacist.

Frequently asked questions about Staphylex 500

What should I do if I miss a dose of Staphylex 500?

If you miss a dose of Staphylex 500, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue on your regular schedule. Do not take a double dose to make up for a missed dose.

Can I take Staphylex 500 with food or alcohol?

Yes, you can take Staphylex 500 with food or alcohol. However, it is best to take the medication at the same time each day to maintain a consistent level of the drug in the bloodstream.

What are the most common side effects of Staphylex 500?

The most common side effects of Staphylex 500 are nausea, vomiting, diarrhea, stomach upset, rash, and hives. These side effects are usually mild and go away on their own.

Can I take Staphylex 500 if I am allergic to penicillin?

A: No, you should not take Staphylex 500 if you are allergic to penicillin. Staphylex 500 is a penicillin antibiotic, so people who are allergic to penicillin are also likely to be allergic to Staphylex 500.

What should I do if I experience side effects while taking Staphylex 500?

A: If you experience any side effects while taking Staphylex 500, contact your doctor. They will be able to assess the severity of the side effects and recommend appropriate treatment.

How long does it take Staphylex 500 to work?

A: Staphylex 500 usually starts to work within a few days. However, it is important to take the medication for the full course of treatment, even if you start to feel better sooner. This will help to ensure that the infection is completely cleared.

Can I take Staphylex 500 while I am pregnant or breastfeeding?

A: Yes, Staphylex 500 is safe to take during pregnancy and breastfeeding. However, it is always best to talk to your doctor before taking any medication, including Staphylex 500, while you are pregnant or breastfeeding.

What are the most common drug interactions with Staphylex 500?

A: The most common drug interactions with Staphylex 500 are with probenecid, warfarin, methotrexate, aspirin, and NSAIDs. If you are taking any of these medications, be sure to tell your doctor before starting Staphylex 500.

Who should not take Staphylex 500?

Staphylex 500 should not be taken by people who are allergic to penicillin antibiotics or to any of the ingredients in Staphylex 500.

Staphylex 500 should also be used with caution in people with liver disease or kidney disease.

Conclusion

Staphylex 500 is an effective antibiotic that can be used to treat a variety of infections caused by PSSA. However, it is important to be aware of the potential side effects and drug interactions before taking Staphylex 500. If you have any questions or concerns, be sure to talk to your doctor.

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