Nexpro RD 40 Capsule SR is a prescription medicine used to treat gastroesophageal reflux disease (Acid reflux) and indigestion by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid in the stomach and promotes easy passage of gas to reduce stomach discomfort.
Nexpro RD 40 Capsule SR is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends.
If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Most common side effects are diarrhea, flatulence, stomach pain, dryness in mouth, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects.
It may also cause sleepiness and dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver diseases so that your doctor can prescribe a suitable dose for you.
How Nexpro Rd 40 Capsule Work
Nexpro RD 40 Capsule SR is a combination of two medicines: Domperidone and Esomeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach.
Esomeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Benefits of Nexpro Rd 40 Capsule
In Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Nexpro RD 40 Capsule SR reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Side Effects of Nexpro Rd 40 Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nexpro RD
- Diarrhea
- Flatulence
- Stomach pain
- Dryness in mouth
- Headache
- Fundic gland polyps
Dosage of Nexpro Rd 40 Capsule
Overdose
The symptoms of an overdose of Nexpro RD 40 capsules include nausea, vomiting, indigestion, diarrhea, constipation, weakness, confusion, agitation, anxiety, fits, altered consciousness, sleepiness, etc. If you think you have taken an excessive dose of this medicine, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you have missed any dose of Nexpro RD 40 capsule, take it as soon as you remember. If it’s time for your next dose, skip the missed dose and continue with your next scheduled dose. Do not take a double dose of this medicine to compensate for the missed one.
Safety Advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Nexpro RD 40 Capsule SR. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Nexpro RD 40 Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Nexpro RD 40 Capsule SR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Nexpro RD 40 Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Nexpro RD 40 Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Nexpro RD 40 Capsule SR may be needed. Please consult your doctor.
Liver
CAUTION
Nexpro RD 40 Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Nexpro RD 40 Capsule SR may be needed. Please consult your doctor.
Use of Nexpro RD 40 Capsule SR is not recommended in patients with moderate and severe liver disease.
Use of Nexpro RD 40 Capsule SR is not recommended in patients with moderate and severe liver disease.
Interactions of Nexpro Rd 40 Capsule
Interactions with other medicines
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Since Nexpro RD 40 mg capsule contains a combination of two components, any interactions with these two components when taken alone may occur with this combination.
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Nexpro RD 40 capsule should not be taken along with anti-HIV medicines such as Nelfinavir, muscle relaxants such as Amiodarone, antibiotics like Clarithromycin, antifungals like Ketoconazole and antihypertensive such as Verapamil.
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This capsule should also not be taken along with medicines used to treat heart problems (Quinidine, Sotalol), medicines used for psychiatric illness (Haloperidol, Citalopram), antifungals (Pentamidine), antimalarials (Halofantrine, Lumefantrine), medicines used to treat allergies (Mizolastine), used in cancer (Toremifene, Vandetanib), gastric emptying medicines (Cisapride) and other medicines like Diphemanil and Methadone.
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Concomitant use of this capsule along with medicines used to treat psychiatric illness (Diazepam), used to treat fits (Phenytoin) is not recommended as it may increase the side effects of this capsule.
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Digoxin which is used to treat heart failure may lead to toxicity when taken with this capsule.
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Blood thinners such as Warfarin if taken along with this medicine can increase the chances of bleeding.
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Other medicines like Rifampicin, Methotrexate, Tacrolimus, Voriconazole, Cilostazol, Clopidogrel, Azithromycin, St John’s wort, etc should be used cautiously.
Interactions with food items
Nexpro RD 40 capsule should preferably be taken on an empty stomach at least 1 hour before meals to enhance effectiveness.
Talk to your doctor if
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You have any liver or kidney-related diseases.
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You are experiencing stomach pain, indigestion, weight loss, difficulty in swallowing, throwing out food or blood after taking this capsule.
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You had fractures or have a bone-related disorder such as osteoporosis or taking steroids.
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You have a heart-related disorder and you often experience symptoms like palpitations, difficulty in breathing and unconsciousness.
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You are supposed to take capsules for long-term treatment (more than three months). Your blood magnesium levels may decrease. Hence your doctor may prescribe regular tests for the same.
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You develop skin eruptions especially in the sun-exposed area after taking this medicine.
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You have a vitamin B12 deficiency as this medicine can reduce the absorption of vitamin B12 after long-term use.
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Taking Nexpro RD 40 capsule for more than one year may increase the chances of developing bone fractures.
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Nexpro RD 40 capsule may lead to a slightly increased risk of bacterial infections due to Salmonella and Campylobacter.
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This medicine is not recommended for patients below 18 years of age.
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Frequent Asked Questions about Nexpro RD 40
What does Nexpro RD 40 capsule contain?
Nexpro RD 40 capsule is an anti-reflux medicine containing a combination of Esomeprazole and Domperidone, used for the treatment of adult patients with gastroesophageal reflux disease (GERD).
What is Nexpro RD 40 capsule used for?
Nexpro RD 40 capsule is used to treat gastroesophageal reflux disease (GERD) in adults. GERD is characterised by heartburn and chest discomfort due to acid regurgitating from the stomach into the food pipe.
Can I take Nexpro RD 40 capsule after food?
No, Nexpro RD 40 capsule should be taken before food as food interacts with the absorption of this medicine. Hence, it should preferably be taken at least 1 hour before food for it to work effectively.
How does Nexpro RD 40 capsule work?
Esomeprazole present in this capsule blocks a pump in the stomach walls and thus reduces acid production. Domperidone improves the mortality of food in the gut. Thus, it prevents it from coming back to the food pipe.
Can I drink alcohol while taking Nexpro RD 40 mg capsule?
You should avoid consuming alcohol while on treatment with Nexpro RD 40 capsule.
Is Nexpro RD 40 capsule to be taken before food?
Yes, Nexpro RD 40 mg capsule should be taken before food (at least an hour before meals).
What time of the day shall I take Nexpro RD 40 capsule?
It is recommended to take Nexpro RD 40 capsule at least 30 mins before the first meal or to take it on an empty stomach.
Is it safe to use Nexpro RD 40 capsule?
Nexpro RD 40 capsule is safe if you take it according to the dose and duration advised by your doctor. If you stop taking this tablet once you start feeling good, the chance of recurrence of the symptom increases.
Can we take Nexpro RD 40 capsule and Itraconazole?
You should avoid taking Nexpro RD 40 capsule with Itraconazole as it reduces the absorption of Itraconazole, reducing its effect. You should consult your doctor before taking Itraconazole when on treatment with this medicine.
Can I take Nexpro RD 40 twice a day?
Follow the exact dose and duration prescribed by the doctor. Do not stop or modify the dose on your own.
Can Nexpro RD 40 cause diarrhoea?
Yes, you might experience diarrhoea as a common side effect of this medicine. So keep yourself hydrated to replace the lost fluids. If you feel these symptoms persistently then immediately talk to your doctor.
How can I manage my condition with lifestyle changes?
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A change in lifestyle will probably help you control and manage acid reflux and related symptoms well.
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Avoid alcohol and smoking, excessive consumption of soft drinks, citrus juices, tea and coffee (caffeinated drinks).
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Avoid spicy, oily and fast foods.
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Never eat late at night or just before going to bed.
How long can we use Nexpro Rd 40?
You can use Nexpro Rd for as long as a doctor has advised you. Do not exceed the maximum daily doses and treatment durations recommended. If you feel like it is not working anymore, talk to your doctor. But do not take it endlessly on your own.
When should I take Nexpro Rd 40?
You should take Nexpro Rd 40 before meals or as advised by the doctor. It would be best if taken in the morning.
Can Nexpro RD 40 capsule be used for treating allergies?
No, Nexpro RD 40 is an acidity medicine. It does not have any anti-allergic actions. It should not be used for the treatment of allergies.
Can I take Nexpro RD for gastritis?
Yes, it is effective in treating gastritis, but only if prescribed by the doctor. Based on the cause and your medical history, your doctor shall prescribe the same. Do not self-medicate.
What are Nexpro rd 40 side effects?
Headache, dizziness, nausea, vomiting and bloating are a few common side effects of Nexpro rd. However, these symptoms are usually mild and resolve on their own. Also, it is not important that everyone experience the same.
What is the action of tab Nexpro rd?
Nexpro RD 40 mg capsule is a combination of two components – Esomeprazole and Domperidone and it works via the combined action of these components. Esomeprazole belongs to the class of medicines called proton pump inhibitors. The lining of the stomach secretes acid by certain processes that involve the intake of ions via proton pumps in the cells.
Esomeprazole reduces the intake of the ions in the stomach cells that are necessary for the production of digestive acids in the stomach and hence leads to reduced acid production. Domperidone acts by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.
Can I take Nexpro rd 40 for acidity?
Yes, Nexpro RD 40 can be used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, etc. However, it is advised to take this medicine only after consulting a doctor.
What is the difference between Nexpro rd 40 and Nexpro fast 40?
Nexpro Fast contains esomeprazole, while Nexpro rd 40 contains a combination of medicines containing esomeprazole and domperidone, as its active ingredients. Based on the cause and your medical history, your doctor shall prescribe one of these medicines. Do not self-medicate.
Is long term use of Nexpro rd 40 safe?
Nexpro rd 40 is safe for long-term use, for as long as the doctor has prescribed you. But if your condition does not improve even after 14 days of taking this medicine, then speak to your doctor. Do not take it endlessly on your own without consulting a doctor.
Summary
- You have been prescribed Nexpro RD 40 Capsule SR for the treatment of acidity and heartburn.
- Take it one hour before the meal, preferably in the morning.
- It is a well-tolerated medicine and provides relief for a long time.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
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