ADC

Africa Digital Clinic

AFRICA DIGITAL CLINIC, we are responsible for your health

Kremil-S: Effective Drug for Relieving Heartburn and Gas

Table of Contents

Kremil-S is a brand of antacid and antiflatulent medication. It is available in two forms: Kremil-S Tablet and Kremil-S Advance.

Types of Kremil-S

  • Kremil-S Tablet is a combination of antacids, aluminum hydroxide and magnesium hydroxide, which effectively increase gastric pH by neutralizing the acid produced in the stomach. It also contains simeticone, a water-repellant with low surface tension used to relieve bloating and gassiness by causing small bubbles to coalesce to large bubbles, which are passed more easily.
  • Kremil-S Advance is a combination of antacid, calcium carbonate and magnesium hydroxide, and histamine H2-receptor antagonist, famotidine. It provides quick and long-lasting relief of heartburn associated with acid indigestion and hyperacidity. Calcium carbonate and magnesium hydroxide quickly neutralize the acidity of the stomach, while famotidine reduces acid production in the stomach for up to 12 hours.
Kremil-S: Effective Drug for Relieving Heartburn and Gas
Kremil-S: Effective Drug for Relieving Heartburn and Gas

Composition of Kremil-S

  • Kremil-S Tablet: Each tablet contains aluminum hydroxide 200 mg, magnesium hydroxide 200 mg, and simeticone 20 mg.
  • Kremil-S Advance: Each tablet contains calcium carbonate 321 mg, magnesium hydroxide 71 mg, and famotidine 10 mg.

Mechanism of action

Kremil-S works by neutralizing stomach acid and relieving gas.

This product contains a combination of antacids, Aluminum Hydroxide and Magnesium Hydroxide, which effectively increase gastric pH by neutralizing the acid produced in the stomach.
This product also contains Simeticone, a water-repellant with low surface tension used to relieve bloating and gassiness by causing small bubbles to coalesce to large bubbles, which are passed more easily.

Antacids

Antacids work by neutralizing stomach acid. They do this by reacting with the acid to form a salt. The salt is then excreted in the urine or stool.

Simeticone

Simeticone is an antiflatulent agent. It works by breaking up gas bubbles in the stomach and intestines. This makes it easier for the gas to pass and be expelled.

Uses of Kremil-S

Kremil-S is used to treat the following conditions:

  • Hyperacidity
  • Heartburn
  • Acid indigestion
  • Sour stomach
  • Bloating
  • Gas

Dosage and administration

Kremil-S Tablet:

  • Adults and children 12 years and older: Chew 1 to 2 tablets after meals and at bedtime, or as needed.
  • Do not take more than 8 tablets in 24 hours.

Kremil-S Advance:

  • Adults and children 12 years and older: Chew 1 tablet as needed, with a maximum of 2 tablets every 24 hours.
  • Do not take more than 4 tablets in 7 days.

Indications/Uses

For the symptomatic relief of hyperacidity associated with peptic ulcer, gastritis, esophagitis and dyspepsia.
As an antiflatulent to alleviate the symptoms of gassiness, including postoperative gas pain, associated with hyperacidity.
As adjunct to H2-blockers or proton pump inhibitors for the rapid relief of ulcer symptoms.
Missed Dose: If the patient misses a dose, just give the next dose and the subsequent doses at the recommended time or schedule.
Do not double the dose unless recommended by a doctor.

Overdosage

Signs and Symptoms of Overdosage: Aluminum Hydroxide may accumulate in bones, lungs and nerve tissues in patients with kidney failure. Large doses or chronic use of Aluminum may also cause phosphorus depletion which is characterized by anorexia, malaise, and muscle weakness. Prolonged use may cause kidney stones, osteomalacia (softening of the bones) and osteoporosis.
Hypotension, nausea, vomiting, ECG change, respiratory or mental depression, and coma have also been reported with large doses of Magnesium in patients with severe kidney disease.
Simeticone overdosage is not expected to cause any clinically important effects.
If the patient has taken more than the recommended dosage, consult a doctor.

Side effects and interactions

Kremil-S is generally safe and well-tolerated. However, some people may experience side effects such as constipation, diarrhea, and stomach upset.

Kremil-S may interact with certain medications, such as antibiotics, tetracycline, and digoxin. It is important to talk to your doctor before taking Kremil-S if you are taking any other medications.

Contraindications

Allergy to any ingredient in the product.
If the patient has: Kidney disease, Intestinal obstruction, Appendicitis, Fecal impaction, Gastric outlet obstruction, Constipation, Phosphate depletion and low serum phosphate, Osteomalacia (softening of bones).

Special Precautions

Patients with advanced kidney disease are at risk of Aluminum and Magnesium accumulation and toxicity. Do not use these products in such patients.
Phenylketonurics: This product contains Phenylalanine as one of the metabolites of Aspartame.
Consult the doctor: Ask a doctor before use if the patient is: Pregnant or breastfeeding.
Taking other medicines; antacids may interact with certain medicines.
Stop use and ask a doctor if the patient needs to take this product for more than 14 days.

Use In Pregnancy & Lactation

Ask a doctor before use if the patient is pregnant or breastfeeding.

Adverse Reactions

The combination of Aluminum Hydroxide and Magnesium Hydroxide balances the side effects of diarrhea from Magnesium Hydroxide and constipation from Aluminum Hydroxide.
Excessive doses of Aluminum Hydroxide and Magnesium Hydroxide may result in high Aluminum and Magnesium levels in the blood in patients with kidney impairment.

Drug Interactions

Antacids decrease the absorption of Tetracycline and Iron. Take Tetracycline 1 hour before or 2 hours after antacids and 2 hours before or 3 hours after Iron-containing preparations.
Antacids may decrease the absorption of orally administered Digoxin, or Indomethacin, Isoniazid, Quinolones (e.g., Ciprofloxacin, Ofloxacin), Ketoconazole. Doses of these drugs should be spaced as far apart as possible from doses of antacids.
Antacid-induced changes in urine pH increase urinary excretion and decrease blood concentration of salicylates such as Aspirin.
Antacid-induced increases in urine pH may decrease excretion of weakly basic drugs (e.g., Quinidine, Chlorpromazine, Propranolol, Diazepam) and increase excretion of weakly acidic drugs (e.g., Phenytoin, Pentobarbital, Warfarin).
Aluminum-Magnesium antacid combination is reported to increase the absorption of Dicumarol, Diazepam and Pseudoephedrine.
Magnesium and Aluminum Hydroxide administration may decrease the rate of Chlordiazepoxide absorption.
Antacids reduce the bioavailability of bisphosphonates (e.g., Alendronate, Etidronate, Risedronate).

Frequent Asked Questions

What is the difference between Kremil-S Tablet and Kremil-S Advance?

Kremil-S Tablet is a combination of antacids and simeticone. Kremil-S Advance is a combination of antacids, simeticone, and famotidine. Famotidine is a histamine H2-receptor antagonist, which means that it reduces the production of stomach acid.

How often should I take Kremil-S?

Follow the dosage instructions on the label. Do not take more than the recommended dosage.

Can I take Kremil-S with other medications?

Talk to your doctor before taking Kremil-S if you are taking any other medications, as it may interact with them.

Is Kremil-S safe for pregnant and breastfeeding women?

Kremil-S is generally considered safe for pregnant and breastfeeding women. However, it is always best to talk to your doctor before taking any medication during pregnancy or breastfeeding.

What should I do if I overdose on Kremil-S?

If you overdose on Kremil-S, seek medical attention immediately.

Conclusion

Kremil-S is a safe and effective antacid and antiflatulent medication. It is available in two forms: Kremil-S Tablet and Kremil-S Advance. Kremil-S Tablet is a good option for people who mostly experience gas and bloating. Kremil-S Advance is a good option for people who mostly experience heartburn.

Also read

The codes will be shown below

Seconds
First: 170598
Seconds
Second: 180198

Featured Articles

Leave a Reply

Your email address will not be published. Required fields are marked *

error: Content is protected !!